Diabetes Chronic Complications

Diabetes is one of the most epidemic disease worldwide. Chronic Hyperglycemic conditions is responsible for the appearance of various organ and tissue damage in diabetic patients. Kidneys, eyes  and peripheral nerves are frequently damaged due to diabetes-specific alteration in microvessels. Furthermore, large vessels are also damaged causing other diseases such as myocardial infarction, cerebral infarction and gangrene. The pathogenesis of these alterations in small and large vessels has been studied and different metabolic abnormalities induced by hyperglycemia are proposed to play a major role in the development of these diabetic vascular complications. 

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